A type of bone tumor characterized by massive destruction of bone near the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee — the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth. It causes pain and restricts movement. Treatment is by surgery, usually followed by chemotherapy.
There is no evidence that the tumor cells themselves are capable of bone destruction; instead, the tumor cells stimulate the formation of cells that function like osteoclasts and resorb bone.
The term “giant cell” reflects the fact that osteoclasts are large multinucleate cells (cells with more than one nucleus) that look gigantic when viewed magnified through a microscope.
Malignant giant cell tumor, known also as giant cell tumor of bone, has been called osteoclastoma, reflecting the long-held incorrect view that the tumor cells are themselves osteoclasts.
A fish about which there are several health concerns. One concern involves carbon monoxide that prevents the flesh of the fish from discoloring and keeps it red. The FDA permits this practice in the US but Japan, Canada and the European Union have banned the practice because of fears that it could be used to […]
- Tunica albuginea
The whitish membrane within the penis that surrounds the spongy chambers (corpora cavernosa). The tunica albuginea helps to trap the blood in the corpora cavernosa, thereby sustaining erection of the penis.
- Tunica albuginea of the testis
The layer of dense whitish inelastic tissue that surrounds the testis.
- Tunnel vision
Loss of peripheral vision with retention of central vision, resulting in a constricted circular tunnel-like field of vision. And, by extension, any very narrow point of view. Also called tubular vision.
A bone in the nose that is situated along the side wall of the nose and is covered by mucous membrane.