Turcot syndrome


A genetic disease characterized by polyps in the colon (large intestine) in addition to tumors in the brain. The polyps in the colon tend to become malignant. The brain tumors are also malignant. Skin abnormalities can also occur. Turcot syndrome is inherited in an autosomal recessive manner and can result from mutations in either the adenomatous polyposis coli (APC) gene or the mismatch repair genes underlying the syndrome of hereditary nonpolyposis colon cancer (HNPCC).

Read Also:

  • Turf toe

    An injury to the big toe due to forced hyperextension (upward bending back) of the toe. The damage is to the capsule of the joint (the first metatarsophalangeal joint) and the ligaments that connect the big toe to the foot. Hyperflexible shoes predispose to the injury. The big toe is painful, tender and swollen. Treatment […]

  • Turgor

    The degree of elasticity of skin, sometimes referred to as skin turgor. The assessment of skin turgor is used clinically to determine the extent of dehydration, or fluid loss, in the body. The measurement is done by pinching up a portion of skin (often on the back of the hand) between two fingers so that […]

  • Turmeric

    A spice with anti-inflammatory effects. The active ingredient is curcumin, which has antioxidant and anti-inflammatory properties. Turmeric is a common ingredient in curry powder. Alternate spellings tumeric.

  • Turner syndrome

    The most common sex chromosome disorder in females, characterized by short stature, webbed neck, broad shield-like chest, wide-spaced nipples, increased carrying angle at the elbow (cubitus valgus), short fourth finger, and malformations of the heart and aorta. The intelligence of those with Turner syndrome is usually within the normal range. Girls with Turner syndrome at […]

  • Twelfth cranial nerve

    The hypoglossal nerve. The twelve cranial nerves, including the hypoglossal nerve, emerge from or enter the skull (the cranium). The hypoglossal nerve supplies the muscles of the tongue. Paralysis of the hypoglossal nerve affects the tongue. It impairs speech (it sounds thick) and causes the tongue to deviate toward the paralyzed side. In time, the […]


Disclaimer: Turcot syndrome definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.