Biochemistry. any substance that interferes with growth of an organism by competing with or substituting for an essential nutrient in an enzymatic process.
Pharmacology. of or relating to certain substances used to prevent or reduce the proliferation of cells, especially cancer cells, by interfering with normal metabolic activity.
any drug that acts by disrupting the normal growth of a cell. Sulfonamide drugs are antimetabolites and some antimetabolites are used in cancer treatment

antimetabolite an·ti·me·tab·o·lite (ān’tē-mĭ-tāb’ə-līt’, ān’tī-)
A substance that closely resembles an essential metabolite and competes with, interferes with, or replaces the metabolite in physiological reactions.


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