of or relating to a gene that is derived from rna or complementary dna, is inserted in reverse orientation into a strand of dna, and is used in genetic engineering to regulate genetic expression of a trait.

antisense an·ti·sense (ān’tē-sěns’, ān’tī-)
of, relating to, or being nucleotide sequences that mimic dna sequences but cannot serve as a template for mrna, thus serving to disrupt genetic replication.
(ān’tē-sěns’, ān’tī-)
relating to a nucleotide sequence that is complementary to a sequence of messenger rna. when antisense dna or rna is added to a cell, it binds to a specific messenger rna molecule and inactivates it.

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