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noun, Chemistry.
the replacement of an atom or group of atoms in a compound by another atom or group.


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  • Substitution therapy

    substitution therapy n. Replacement therapy in which a substitute substance is used.

  • Substitution transfusion

    substitution transfusion n. See exchange transfusion.

  • Substitutive

    [suhb-sti-too-tiv, -tyoo-] /ˈsʌb stɪˌtu tɪv, -ˌtyu-/ adjective 1. serving as or capable of serving as a substitute. 2. pertaining to or involving substitution. substitutive /ˈsʌbstɪˌtjuːtɪv/ adjective 1. acting or able to act as a substitute 2. of or involving substitution

  • Substitutivity

    /ˌsʌbstɪtjuːˈtɪvɪtɪ/ noun 1. (logic, philosophy) the principle that expressions with the same reference can be substituted for one another without affecting the truth-value of any context in which they occur See also transparent context, opaque context

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