Adams-Stokes disease


Adams-Stokes disease: Sudden collapse into unconsciousness due to a disorder of heart rhythm in which there is a slow or absent pulse resulting in syncope (fainting) with or without convulsions.

In this condition, the normal heartbeat passing from the upper chambers of the heart to the lower chambers is interrupted. This results in a condition called a “heart block.” When a heart block occurs, the heart rate usually slows considerably. This can cause inadequate blood flow to the brain and result in fainting.

This condition goes by a baffling number of names including the Adams-Stokes, Morgagni, Morgagni-Adams-Stokes, Spens syndrome, and Stokes-Adams disease or syndrome. Roberts Adams (1791-1875) and William Stokes (1804-1878) were Irish physicians. Stokes is also remembered for Cheyne-Stokes respiration, a pattern of breathing characteristically seen in coma. Thomas Spens (1764-1842) was a Scottish physician. Giovanni Battista Morgagni (1682-1771) was an Italian anatomist and pathologist. Although Adams, Stokes, and Spens did describe the syndrome (separately) in the early 19th century, the first description was, in fact, recorded in 1761 by Morgagni. All of these eponyms are now declining in use as our understanding of the disease process advances.

The preferred name is cardiovascular syncope.

Read Also:

  • ADAMTS2

    ADAMTS2: A gene that encodes a metalloproteinase enzyme. This enzyme is responsible for processing type I, type II, and type V procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off of one end of […]

  • Adapter protein

    Adapter protein: A protein acts as a connecting molecule. An adapter protein is critical to intermolecular interactions and plays a role in the regulation of signal transduction initiated by engagement of surface receptors on all cell types. Some adapter proteins are expressed in all tissues, while the expression of other adapter proteins is restricted to […]

  • ADCC (antibody-dependent cell-mediated cytotox.)

    ADCC (antibody-dependent cell-mediated cytotoxicity): An immune response in which antibodies, by coating target cells, makes them vulnerable to attack by immune cells. Antibody-dependent cell-mediated cytotoxicity is commonly (and blissfully) abbreviated ADCC.

  • ADD (attention deficit disorder)

    ADD (attention deficit disorder): ADHD is a common condition that affects children and adolescents, while ADD is more common in adults. ADHD is the most commonly diagnosed mental disorder of children and is more common in boys than in girls. Children with ADHD generally have greater problems paying attention or concentrating. They can’t seem to […]

  • Addiction

    Addiction: An uncontrollable craving, seeking, and use of a substance such as alcohol or another drug. Dependence is such an issue with addiction that stopping is very difficult and causes severe physical and mental reactions.


Disclaimer: Adams-Stokes disease definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.