Angiopathy: Disease of the arteries, veins, and capillaries. There are two types of angiopathy: microangiopathy and macroangiopathy. In microangiopathy, the walls of small blood vessels become so thick and weak that they bleed, leak protein, and slow the flow of blood. For example, diabetics may develop microangiopathy with thickening of capillaries in many areas, including the eye. In macroangiopathy, fat and blood clots build up in the large blood vessels, stick to the vessel walls, and block the flow of blood. Macroangiopathy in the heart is coronary artery disease; in the brain, it is cerebrovascular disease. Peripheral vascular disease is macroangiopathy that affects, for example, vessels in the legs.
Angioplasty: Procedure with a balloon-tipped catheter to enlarge a narrowing in a coronary artery. Also called Percutaneous Transluminal Coronary Angioplasty (PTCA).
Angiosarcoma: A form of tissue cancer (sarcoma) that arises in the lining of blood vessels. Angiosarcomas tend to be aggressive, recur locally, and spread widely. Predisposing factors include lymphedema (as from a radical mastectomy), radiotherapy, foreign materials (such as steel and plastic) in the body, and environmental agents (such as arsenic solutions used to spray […]
Angiostatin: A fragment of a protein, plasminogen, that is involved in blood clotting. Angiostatin is normally secreted by tumors, and it appears to halt the process of developing new blood vessels, which is necessary to tumor development.
Angiostrongyliasis: Infection with the parasitic nematode (roundworm) Angiostrongylus. The two species that infect humans are A. cantonensis and A. costaricensis. A. cantonensis, the rat lungworm, is the most common cause of human eosinophilic meningitis (meningitis with eosinophils in the cerebrospinal fluid). The meningitis is due to the presence of the rat lungworm larvae in the […]
- Angiostrongylus infection
Angiostrongylus infection: Also called angiostrongyliasis. See: Angiostrongyliasis.