APC: APC has several very different meanings in medicine. See each of the following separate entries:
1. APC (gene).
2. APC (immunology).
3. APC (medication).
- APC (gene)
APC (gene): A major gene that is involved in causing colorectal cancer. APC is involved in both sporadic and familial forms of colorectal cancer. A mutation in the APC gene is the earliest detectable molecular abnormality in colorectal cancer. This mutation imitates the neoplastic process 20 to 30 years before the malignancy itself is full-blown. […]
- APC (immunology)
APC (immunology): Antigen-presenting cell, a cell that can “present” antigen in a form that T cells can recognize it. Among the APCs are B cells and cells of the monocyte lineage including macrophages.
- APC (medication)
APC (medication): Aspirin, phenacetin, and caffeine (a pill containing all three). Phenacetin was the first nonsteroidal anti-inflammatory drug (NSAID) to be associated with kidney failure.
- APECED (autoimmune polyendocrinopathy)
APECED (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy): A genetic autoimmune disease with an extraordinary array of clinical features but characterized most often by at least 2 of the following 3 findings: hypoparathyroidism — underfunction of the parathyroid glands which control calcium, candidiasis (yeast infection), and adrenal insufficiency (underfunction of the adrenal gland). APECED was the first systemic (bodywide) […]
- Apert syndrome
Apert syndrome: A malformation syndrome characterized by a high short skull, underdevelopment of the midface, soft tissue and bony (“mitten glove”) fusion of fingers and toes, fusion of the neck vertebrae, and varying degrees of developmental delay/mental retardation. The frequency of the syndrome rises with the age of the father reflecting the fact that the […]