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APM1

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• Apnea, central sleep

  Apnea, central sleep: Sleep apnea is a breathing disorder characterized by brief interruptions of breathing during sleep. It owes its name to a Greek word, apnea, meaning “want of breath.” There are two types of sleep apnea: central and obstructive. Central sleep apnea occurs when the brain fails to send the appropriate signals to the […]

• Apnea, obstructive sleep

  Apnea, obstructive sleep: Sleep apnea is a breathing disorder characterized by brief interruptions of breathing during sleep. It owes its name to a Greek word, apnea, meaning “want of breath.” There are two types of sleep apnea: central and obstructive. Central sleep apnea occurs when the brain fails to send the appropriate signals to the […]

• ApoA-I Milano

  ApoA-I Milano: A variant of apolipoprotein A-I identified in about 40 inhabitants of Limone sul Garde, a small town in rural North Italy, who had extraordinarily low HDL levels, levels so low that they were off the scale. Because HDL is the “good” cholesterol, it was expected that these people would have very high rates […]

• APOBEC3G

  APOBEC3G: A human protein that interferes with the replication of HIV by incorporating itself into virus particles and damaging the genetic material of the virus. The viral protein Vif can halt this process in two ways: (1) by binding to APOBEC3G and preventing it from incorporating into virus particles; and (2) by targeting APOBEC3G for […]

• Apolipoprotein A-I

  Apolipoprotein A-I: APOA-I. The major protein component of HDL (high density lipoprotein) and a relatively abundant plasma protein. APOA-I is instrumental in promoting the transfer of cholesterol into the liver where it is metabolized and then excreted via the intestine from the body. The gene locus for APOA-I is on chromosome 11q23. A number of […]

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