Base excision repair
Base excision repair: A process of DNA repair in which an altered base is excised (removed) by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is then filled in by the sequential action of DNA polymerase and DNA ligase. Abbreviated BER.
Read Also:
- Base in DNA
Base in DNA: A unit of the DNA. There are 4 bases: adenine (A), guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is the genetic code.
- Base of tongue
Base of tongue: The back third of the tongue. In contrast to the anterior tongue, which is the front two-thirds of the tongue. The distinction between the anterior and base of the tongue reflects the fact that they are of different embryological origin. The distinction also matters as regards cancer. See: Tongue cancer.
- Base pair
Base pair: Two DNA bases that are complementary to one another (A and T, or G and C) and join in strands to form the double-helix that is characteristic of DNA.
- Base sequence
Base sequence: The particular order of nucleotide bases in a DNA molecule.
- Base sequence analysis
Base sequence analysis: A method for determining the order of nucleotide bases in DNA.