Chancre: The classic painless ulcer of syphilis. The chancre forms in the first (primary) stage of syphilis. It is highly contagious and can last 1-5 weeks. The disease can be transmitted from contact with the ulcer, which is teeming with spirochetes. If the ulcer is outside of the vagina or on the scrotum of the male, the use of condoms may not help in preventing transmission of the disease. Likewise, if the ulcer is in the mouth, merely kissing the infected individual can spread syphilis.
The word chancre is the French for a little ulcer. Chancre and the English canker come from the Latin cancer for crab. Why? Perhaps because chronic ulcers can be hard like the shell of a crab.
Chancroid: A sexually transmitted infection (STI) caused by the bacterium Haemophilus ducreyi. Periodic outbreaks of chancroid have occurred in the US, usually in minority populations in the inner cities. This disease is common in sub-Saharan Africa among men who have frequent contact with prostitutes. The infection begins with the appearance of painful open sores on […]
- Chandipura virus
Chandipura virus: A virus that causes fever, symptoms similar to those of flu, and acute encephalitis (inflammation of the brain). Chandipura virus was first isolated in 1965 in a village in Maharashtra State, India. Since then, the virus has been reported in adjoining states in central India. The likely vector (carrier) of the virus is […]
- Change, single base
Change, single base: A change in which a single base in the DNA differs from the usual base at that position. These single base changes are also called SNPs or “snips.” Millions of SNP’s have been cataloged in the human genome. Some SNPs such that which causes sickle cell are responsible for disease. Other SNPs […]
Channelopathy: A disease involving dysfunction of an ion channel. Channelopathies are known that involve the ion channels for potassium, sodium, chloride and calcium. There are also channelopathies involving the acetylcholine receptor, the glycine receptor, and other receptors. Each channelopathy can play a role in a number of different diseases. For example, the calcium channelopathies include […]
Chaperone: 1. Any protein that is required for the proper folding or assembly of another protein or protein complex without being a component of the final structure. 2. A woman who is present when a male physician examines a female patient. 3. Anyone present when a physician examines a patient of the opposite sex from […]