Corticosteroid allergy: A delayed allergic reaction to corticosteroid (drugs similar to cortisone). This occurs in 1-4% of people who use corticosteroids for asthma or other allergic diseases. A positive patch test to a corticosteroid means the patient cannot use that particular steroid. Although cross allergy between corticosteroids is common, such patients usually can tolerate another corticosteroid.
- Corticotropin-releasing hormone
Corticotropin-releasing hormone: A hormone made by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary gland. Corticotropin-releasing hormone is abbreviated and often referred to as CRH. CRH is chemically classed as a neuropeptide hormone — a protein-like molecule made up of a short chain of amino acids produced in the brain that […]
Cortisol: A metabolite of the primary stress hormone cortisone. Cortisol is an essential factor in the proper metabolism of starches, and it is the major natural glucocorticoid (GC) in humans.
Cosmid: DNA from a bacterial virus into which is spliced a small fragment of a genome to be amplified and sequenced. A cosmid is an artificially constructed structure. It is used in cloning (copying) pieces of DNA. (On a technical level, a cosmid contains the cos gene of phage lambda and can be packaged in […]
- Costal margin
Costal margin: The lower edge of the chest (thorax), formed by the bottom edge of the rib cage.
Inflammation and swelling of the cartilage of the chest wall, usually involving the cartilage that surrounds the breastbone (sternum) but sometimes including the adjacent tip of a rib. Costochondritis causes local pain and tenderness of the chest around the sternum. Treatment options include anti-inflammatory medications and, in severe cases, corticosteroid injections. Also known as Tietze […]