Gene, candidate
Gene, candidate: Any gene thought likely to cause a disease. The gene may be a candidate because it is located in a particular chromosome region suspected of being involved in the disease or its protein product may suggest that it could be the disease gene in question.
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- Gene, evolutionarily conserved
Gene, evolutionarily conserved: A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. Changes in the gene are likely to be lethal.
- Gene, marker
Gene, marker: A detectable genetic trait or segment of DNA that can be identified and tracked. A marker gene can serve as a flag for another gene, sometimes called the target gene. A marker gene must be on the same chromosome as the target gene and near enough to it so that the two genes […]
- Gene, Med1 DNA repair
Gene, Med1 DNA repair: A gene that codes for one of the key enzymes involved in repairing DNA. The DNA in genes is constantly mutating and being repaired. This repair process is controlled by special genes. A mutation in a DNA repair gene such as Med1 can cripple the repair process and cause a cascade […]
- Gene, regulatory
Gene, regulatory: A gene that regulates the expression of other genes. A regulatory gene is a nosy gene whose prime preoccupation is to horn in on other genes and control the rate at which they make products.
- Gene, suicide
Gene, suicide: A gene whose expression in a cell is lethal for that cell. Suicide genes form the basis of a strategy for making cancer cells more vulnerable, more sensitive to chemotherapy. The approach has been to attach parts of genes expressed in cancer cells to other genes for enzymes not found in mammals that […]