Hybridization, nucleic acid


DNA-DNA (DNA can be rendered single-stranded by heat denaturation), DNA-RNA or RNA-RNA.

In situ hybridization involves hybridizing a labelled nucleic acid (often labelled with a fluorescent dye) to suitably prepared cells or histological sections. This is used particularly to look for specific transcription or localization of genes to specific chromosomes via fluorescent in situ hybridization (FISH) analysis).

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