A map of the genes on a chromosome based on linkage analysis. A linkage map does not show the physical distances between genes but rather their relative positions, as determined by how often two gene loci are inherited together. The closer two genes are (the more tightly they are linked), the more often they will be inherited together. Linkage distance is measured in centimorgans (cM).
- Lip, cleft
A fissure in the upper lip that is due to failure of the left and right sides of the fetal lip tissue to fuse, an event that should take place by 35 days of fetal age. Cleft lip can be on one side only or on both sides. Because failure of lip fusion can impair […]
- Lipectomy, suction-assisted
Another name for liposuction, the surgical removal of fat deposits from specific parts of the body, the most common being the abdomen (the “tummy”), buttocks (“behind”), hips, thighs and knees, chin, upper arms, back, and calves. The technique breaks up and “sucks” fat out of the body through a canula (a hollow instrument) inserted subdermally […]
Another word for “fat.” (Please see the various meanings of fat.) A lipid is chemically defined as a substance that is insoluble in water and soluble in alcohol, ether, and chloroform. Lipids are an important component of living cells. Together with carbohydrates and proteins, lipids are the main constituents of plant and animal cells. Cholesterol […]
- Lipid profile
A pattern of lipids in the blood. A lipid profile usually includes the levels of total cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, and the calculated low-density lipoprotein (LDL) ‘cholesterol.
- Lipid storage diseases
A series of disorders due to inborn errors in lipid metabolism resulting in the abnormal accumulation of lipids in the wrong places (Examples include Gaucher, Fabry and Niemann-Pick diseases and metachromatic leukodystrophy).