A neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. The locked-in syndrome is usually a complication of a cerebrovascular accident (a stroke) in the base of the pons in the brainstem. The patient is alert and fully conscious but cannot move. Only vertical movements of the eyes and blinking are possible.
Locked-in syndrome can also be due to traumatic brain injury, demyelinating diseases (disorders in which the insulating material around brain cells is lost), and medication overdose.
There is no cure for locked-in syndrome, nor is there a standard course of treatment. Functional neuromuscular stimulation may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive. The prognosis for those with locked-in syndrome is poor. The majority of patients do not regain function.
Movement from one place to another. And the ability to locomote, to get from one place to the next. The locomotive system permits locomotion and consists of bones that are the framework of the skeleton, joints that hold the bones together and make movement possible, and muscles that contract and relax and make for movement. […]
- Locomotive system
The bones, the joints, and the muscles that contract and relax to move the joints and bones.
Locoregional anesthesia; Locoregional metastasis.
- Locoregional anesthesia
Anesthesia that eliminates pain only in the region of the surgery. This may be done by a “spinal” in which an anesthetic agent is administered by lumbar injection. Locoregional anesthesia is in contrast to general anesthesia on the one hand and local anesthesia on the other.
- Locoregional metastasis
Metastasis (spread) of a cancer only within the region in which it arose. In contrast to systemic metastasis.