An inherited syndrome characterized by aortic aneurysms and other blood vessel abnormalities in children. The condition is often associated with other birth defects. The aortic aneurysms of Loeys-Dietz syndrome are prone to rupture at a smaller size than other aneurysms, with early identification of the condition and surgical intervention critical for survival.
The disease caused by the eye worm known as loa loa, a parasite that lives in humans and other primates. People contract the parasite when bitten by infected deer flies. The larvae of the worm enter the bloodstream and later develop into adult worms. Symptoms may not appear for months or years after the bite […]
- Library, genomic
A collection of clones that is made from a set of randomly generated overlapping DNA fragments and that represents the entire genome of an organism. Also known as clone bank.
- Library, cDNA
A collection of DNA sequences generated from mRNA (messenger RNA) sequences. This type of DNA library contains only DNA that codes for proteins and does not include any non-coding DNA.
- Library, arrayed
In genetics, arrayed libraries of DNA clones are used for many purposes, including screening for a specific gene or genomic region of interest as well as for physical mapping. An arrayed library consists of (in technical terms) individual primary recombinant clones (which are hosted in phage, cosmid, YAC, or another vector) that have been placed […]
- Long-chain-3-hydroxyacyl-CoA dehydrogenase def
Acute fatty liver of pregnancy (AFLP) has been found to be associated in some cases with an abnormality of fatty-acid metabolism. This abnormality is a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenase (LCHAD). The mother (and father) have 50% of normal LCHAD activity and the fetus has no LCHAD activity. The metabolic disease in the baby’s […]