Longitudinal


Along the length of something; running lengthwise or, by extension, over the course of time.

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  • Longitudinal study

    A study done over the passage of time. For example, a longitudinal study of children with Down syndrome might involve the study of 100 children with this condition from birth to 10 years of age. Longitudinal study is the opposite of cross-sectional (synchronic) study. Also known as diachronic study.

  • Longitudinal section

    A section that is cut along the long axis of a structure. Longitudinal section is the opposite of cross-section.

  • Lordosis

    Inward curvature of the spine. The spine is not supposed to be absolutely straight, so some degree of curvature is normal. When the curve exceeds the usual range, it may be due to musculoskeletal disease or simply to poor posture. Treatment usually involves physical therapy, although in severe cases surgery, casting, and/or bracing may be […]

  • Loss-of-function mutation

    A mutation that results in reduced or abolished protein function. Gain-of-function mutations,which are much less common, confer an abnormal activity on a protein.

  • Lou Gehrig disease

    ALS usually leads to death within 5 years of the time the diagnosis of ALS is made; the range is from 2 to 7 years.


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