Maternal age


The age of the mother at the time of delivery. Advanced maternal age is usually defined as age 35 or more at delivery.

Advanced maternal age predisposes to Down syndrome (trisomy 21). The risk of having a Down syndrome baby rises with maternal age. It essentially doubles from 1 in 725 at maternal age 32 to 1 in 365 at maternal age 35. And the risk continues to climb with the years and is 1 in 32 at maternal age 45.

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  • Maternal mortality rate

    The number of registered maternal deaths due to birth- or pregnancy-related complications per 100,000 registered live births.

  • Maternal phenylketonuria

    A mother with the genetic disease phenylketonuria (PKU) whose high blood levels of phenylalanine (phe) are dangerous to a developing fetus. High phe is a teratogen. It can damage a baby before birth. Women with PKU who are off the special PKU diet should restart back it, ideally prior to conception. During pregnancy they must […]

  • Maternal serum alpha-fetoprotein (MSAFP)

    High with open neural tube defects such as anencephaly and spina bifida (meningomyelocele); and Low with Down syndrome (trisomy 21, an extra chromosome number 21). Alpha-fetoprotein production is essentially zero after a year of age. However, it increases again under the stimulus of some liver diseases. It may, for example, be produced by viral hepatitis […]

  • Materteral

    1. Literally, relating to a maternal aunt. 2. Figuratively, suggestive of an aunt on either side of the family. 3 In medical genetics, pertaining to an aunt. An materteral relationship is the genetic relationship between aunts and their nieces and nephews. Materteral is synonymous with materterine. From the Latin matertera meaning maternal aunt, from mater […]

  • Mathematics disorder

    A condition characterized by math skills that are significantly below normal, given the person’s age, intelligence, and education. A mathematics disorder can include problems writing or printing numbers, counting, adding and subtracting, interpreting simple mathematical signs such as +, -, x, and / and learning terms that include numbers. Mathematics disorder often comes to attention […]


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