Pediatric End-Stage Liver Disease. A disease severity scoring system for children under 18 years of age, designed to improve the organ allocation in transplantation based on the severity of liver disease rather than time on the waiting list. The PELD score is based on both laboratory data and growth data. The laboratory values are a patient’s albumin, bilirubin, and international normalized ratio, or INR (a measure of blood-clotting time). These values are used together with the patient’s degree of growth failure to determine the PELD score. The adult version of PELD is called MELD.
- Peliosis hepatis
A rare condition in which the liver contains multiple, randomly-distributed blood-filled spaces or cavities ranging in size from millimeters to several centimeters in diameter. Peliosis hepatis has been associated with the use of anabolic steroids and other hormones such as oral contraceptive pills. It has also been observed in association with both benign and malignant […]
- Pelizaeus-Merzbacher disease
A disorder of the central nervous system (CNS) in which there is loss of myelin, the sheath around the nerves. The disease is clinically characterized by nystagmus (rhythmical oscillation of the eyes), impaired motor development, tremor, progressive spasticity (increased muscle tone), ataxia (wobbliness), choreoathetotic movements, and dysartria (difficulty speaking). Pelizaeus-Merzbacher disease (PMD) in its classical […]
- Pelizaeus-Merzbacher-like disease
A disease that is virtually identical to Pelizaeus-Merzbacher disease (PMD) but without a mutation in the PLP1 gene that causes PMD. Both PMD and Pelizaeus-Merzbacher-like disease (PMLD) are characterized by rapid, involuntary movements of the eye (nystagmus), impaired motor development, ataxia, and difficulty articulating. Some patients with PMLD have diverse mutations in a gene called […]
meat (pork fatback); molasses; and meal (cornmeal). Today pellagra continues to be a problem in developing countries where there is significant malnutrition or where niacin-deficient foods such as corn and rice are the primary sources of nutrition. The puzzle of pellagra was solved by Dr. Joseph Goldberger. Dr. Goldberger was assigned in 1914 by the […]
Having to do with the pelvis, the lower part of the abdomen, located between the hip bones.