Progressive


Increasing in scope or severity, advancing, or going forward. For example, a disease that is progressive is worsening.

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  • Progressive dementia with cerebellar ataxia

    Gerstmann-Straussler-Scheinker syndrome.

  • Progressive infantile poliodystrophy

    A progressive disease of the nervous system characterized by spasticity (tightness), myoclonus and dementia and by liver problems with jaundice and cirrhosis. This disorder, first described by Alpers in 1931 as “Diffuse progressive degeneration of gray matter of cerebrum”, usually begins early in life with convulsions. A continuous seizure (status epilepticus) is often the final […]

  • Progressive multifocal leukoencephalopathy

    A rapidly progressive, often fatal viral infection of the brain. Commonly abbreviated as PML. PML is believed to be due to the Jacob-Creutzfeldt (JC) papovavirus. The virus infects oligodendrocytes (support cells in the brain). The signs and symptoms of PML include headaches, memory loss, changes in mental status, speech and vision difficulties, loss of strength, […]

  • Progressive supranuclear palsy

    A neurologic disorder of unknown origin that gradually destroys cells in many areas of the brain, leading to serious and permanent problems with the control of gait and balance. The most obvious sign of the disease is an inability to aim the eyes properly, which occurs because of damage in the area of the brain […]

  • Progressive vaccinia

    A severe complication of smallpox vaccination that occurs because of an immune defect in the vaccinated individual or in a susceptible contact of that person. In progressive vaccinia, the primary vaccination site does not heal but rather expands with extensive necrosis (death of tissue), eventually covering large portions of body with extensive destruction of normal […]


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