Sex region Y
A region on the Y chromosome that determines the sex of the individual. This region which goes by the symbol SRY (sex region Y) is necessary and sufficient for male sex determination. It is the testis-determining factor.
Mutations in SRY give rise to XY females with gonadal dysgenesis who appear to be normal females at birth, but at puberty do not develop secondary sexual characteristics (breasts, etc.), do not menstruate, and have streak (fibrous) gonads without eggs. There is a high incidence of neoplasia (gonadoblastoma and germinoma) in the streak gonads.
Translocation (transfer) of the part of the Y chromosome containing SRY to the X chromosome results in XX males — individuals who have XX sex chromosomes but appear male.
SRY resides in chromosome band Yp11.3 and encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA binding proteins.
Read Also:
- Sexploitation
The exploitation of sex, often for commercial purposes. The term is a mid-20th century merger of sex and exploitation.
- Sexual child abuse
The diagnosis of sexual child abuse involves a thorough nonjudgmental history of the immediate events as well as a review of potential similar experiences often independently done by a physician, social worker, and the police department. A complete physical exam of the child which may include the taking of photographs to document sexual abuse is […]
- Sexual masochism
Sexual masochism is a disorder in which individuals use sexual fantasies, urges or behaviors involving the act (real, not simulated) of being humiliated, beaten or otherwise made to suffer in order to achieve sexual excitement and climax. These acts may be limited to verbal humiliation, or may involve being beaten, bound or otherwise abused. Masochists […]
- Sexual sadism
Individuals with sexual sadism disorder have persistent fantasies in which sexual excitement results from inflicting psychological or physical suffering (including humiliation and terror) on a sexual partner. This disorder is different from minor acts of aggression in normal sexual activity; for example, rough sex. In some cases, sexual sadists are able to find willing partners […]
- Sexually transmitted disease
Any disease transmitted by sexual contact; caused by microorganisms that survive on the skin or mucus membranes of the genital area; or transmitted via semen, vaginal secretions, or blood during intercourse. Because the genital areas provide a moist, warm environment that is especially conducive to the proliferation of bacteria, viruses, and yeasts, a great many […]