The first lung transplant was done by the American surgeon James Hardy (1918-) in 1964.
- Transplant, renal
Replacement of a diseased, damaged, or missing kidney with a donor kidney. Also called a kidney transplant. Patients with end-stage renal failure are candidates for transplantation. A successful transplant frees the patient from dialysis and provides the kidney’s other metabolic functions. The survival rate a year after a transplant from a living related donor is […]
- Transplantation genetics
class I (HLA-A,B,Cw), class II (HLA-DR,DQ,DP) and class III (no HLA genes). The need for HLA matching depends on the type of transplant. In bone marrow transplantation, HLA matching is an absolute necessity, lest the cells be rejected. In corneal transplantation, HLA matching is less relevant because of the lack of blood vessels in the […]
- Transplantation, peripheral blood stem cell
A technique in which stem cells are obtained from a patient’s blood and used in bone marrow transplantation. Stem cells are small, round cells with a squat nucleus and scant surrounding cytoplasm. Although unremarkable in appearance, stem cells can perform what have been called “acts of biological resurrection.” Whereas other types of cells in the […]
- Transport defect
Within the body, many molecules are able to pass across the membranes that surround cells. These molecules can accomplish this feat due to specific transport systems. These systems include special receptors on the membrane of the cell and special carrier proteins. The receptor recognizes the molecule and receives it on the cell membrane. Then the […]
- Transport disease, cystine
Commonly known as cystinuria, this is an inherited (genetic) disorder of the transport of an amino acid (a building block of protein) called cystine. The result is an excess of cystine in the urine (cystinuria) and the formation of cystine stones.