ZAP-70
Zeta-chain-associated protein kinase 70. A member of the protein tyrosine kinase family, ZAP-70 is normally expressed in T cells and natural killer cells and has a critical role in the initiation of T-cell signaling. ZAP-70 is expressed in T cells and tumors of T-cell lineage. A high level of ZAP-70 expression appears restricted to T-cell proliferative diseases and a subgroup of chronic lymphocytic leukemia (CLL). The ZAP-70 gene is in chromosome 2q12.
Read Also:
- Z chromosome
A sex chromosome in certain animals, such as chickens, turkeys, and moths. In humans, males are XY and females XX, but in animals with a Z chromosome, males are ZZ and females are WZ.
- Prenatal development
The process of growth and development within the womb, in which a single-cell zygote (the cell formed by the combination of a sperm and an egg) becomes an embryo, a fetus, and then a baby. The first two weeks of development are concerned with simple cell multiplication. This tiny mass of cells then adheres to […]
- Nerve, second cranial
Also known as the optic nerve. This nerve connects the eye to the brain and carries the impulses formed by the back layer of the eye (retina) to the brain, which interprets them as images. The cranial nerves emerge from or enter the skull (the cranium), as opposed to the spinal nerves which emerge from […]