ZAP-70


Zeta-chain-associated protein kinase 70. A member of the protein tyrosine kinase family, ZAP-70 is normally expressed in T cells and natural killer cells and has a critical role in the initiation of T-cell signaling. ZAP-70 is expressed in T cells and tumors of T-cell lineage. A high level of ZAP-70 expression appears restricted to T-cell proliferative diseases and a subgroup of chronic lymphocytic leukemia (CLL). The ZAP-70 gene is in chromosome 2q12.

Read Also:

  • Z chromosome

    A sex chromosome in certain animals, such as chickens, turkeys, and moths. In humans, males are XY and females XX, but in animals with a Z chromosome, males are ZZ and females are WZ.

  • Virginal membrane

    A thin membrane which completely or partially occludes the vaginal opening. This fold of mucous membrane is usually present at birth at the orifice of the vagina. In medicine, it is called the vaginal membrane or the hymen. Hymen is a Greek word meaning “skin” or “membrane.” The ancient Greeks applied the word “hymen” to […]

  • Incompetent cervix

    A cervix that has an abnormal tendency to dilate and so may not be able to keep a fetus from being spontaneously aborted (miscarried).


Disclaimer: ZAP-70 definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.