ZAP-70
Zeta-chain-associated protein kinase 70. A member of the protein tyrosine kinase family, ZAP-70 is normally expressed in T cells and natural killer cells and has a critical role in the initiation of T-cell signaling. ZAP-70 is expressed in T cells and tumors of T-cell lineage. A high level of ZAP-70 expression appears restricted to T-cell proliferative diseases and a subgroup of chronic lymphocytic leukemia (CLL). The ZAP-70 gene is in chromosome 2q12.
Read Also:
- Z chromosome
A sex chromosome in certain animals, such as chickens, turkeys, and moths. In humans, males are XY and females XX, but in animals with a Z chromosome, males are ZZ and females are WZ.
- Development, Human, . . . (NICHD)
Development, Human, National Institute of Child Health and (NICHD): One of the US National Institutes of Health, NICHD is in a sense the NIH for kids in that it is concerned with child health. The mission of the NICHD is, in formal terms, to support and conduct “research on fertility, pregnancy, growth, development, and medical […]
- NIDDK (Nat'l Institute of Diabetes and Kidney)
One of the National Institutes of Health in the U.S., the NIDDK has a multisystem name and a comparably broad mission, namely, to “conduct and support basic and applied research and provide leadership for a national program in diabetes, endocrinology, and metabolic diseases; digestive diseases and nutrition; and kidney, urologic, and hematologic diseases. Several of […]