ZAP-70
Zeta-chain-associated protein kinase 70. A member of the protein tyrosine kinase family, ZAP-70 is normally expressed in T cells and natural killer cells and has a critical role in the initiation of T-cell signaling. ZAP-70 is expressed in T cells and tumors of T-cell lineage. A high level of ZAP-70 expression appears restricted to T-cell proliferative diseases and a subgroup of chronic lymphocytic leukemia (CLL). The ZAP-70 gene is in chromosome 2q12.
Read Also:
- Z chromosome
A sex chromosome in certain animals, such as chickens, turkeys, and moths. In humans, males are XY and females XX, but in animals with a Z chromosome, males are ZZ and females are WZ.
- Clinical research trials
Clinical research trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people. Clinical research trials may be conducted by government health agencies such as NIH, researchers affiliated with a hospital or university medical program, independent researchers, or private industry. Usually volunteers are recruited, […]
- Board eligible
Board eligible: In medicine, a description for a physician who has completed the requirements for admission to a medical specialty board examination but has not passed that examination. For example, a physician must have 3 years of training in an approved pediatric residency to be eligible for certification by the American Board of Pediatrics.