Up Syndrome


elaboration of the severity of the condition down syndrome
up syndrome: you got down syndrome so bad, you probably got up, left, and right syndrome too
a condition of extreme smartness
“i’m so smart i have up symdrome.”
the condition where genitalia is in a perpetually happy state.
“tom came down with a case of up-syndrome soon after meeting caroline.”

“we always thought susie was a bit weird, but we didnt know for certain until her secret reared its ugly little head — she was diagnosed with up-syndrome.”

5:00 news report:
“rare condition found in man with up-syndrome… are two p-n-ses better than one?”
1. the state of one’s p-n-s being in a perpetual state of happiness.
“ever since meeting caroline, i think tom has come down with a bout of up-syndrome.”

“…it really sucks having your upsyndrome flair up at a gay bar…”

we always thought susie was weird, then the truth reared its ugly little head — out of her pants when she was diagnosed with up-syndrome!”

5:00 news headline:
“rare condition found in man with up-syndrome — are two p-n-ses better than one?”
having so much down syndrome that you dont even know what is going on. you must have a lot of downs to be able to get upsyndrome. this is a very rare but life threating disease. but by having upsyndrome you are automatically a playa.
guy 1: is that an upsyndrome over there!?
guy 2: duh. he is so dumb. but he is a boss at the same time.
guy 1: word.

Read Also:

  • Upsyndromed

    not having down’s syndrome. jenifer is not upsyndromed.

  • upta

    upta means up to like come upta camp dude what you doing this weekend? oh i dont know come upta camp

  • uptag

    a shorthand, inspired by facebook, as a combination of uploading and tagging friends onto a picture, video, or any media the party last night was crazy dude! don’t forget to uptag me so i can at least remember what happened!

  • up-ta-fucks

    when a person is seen to being ‘up-to-no-good’, they are clueless and have performed something random. the act performed by someone is not required scenario 1: that dude over there is a bit “up-ta-f-cks” ay. scenario 2: your essay looks a bit “up-ta-f-cks” mate. scenario 3: his style is “up-ta-f-cks” hard ay.

  • uptagrafft

    in dutch means higher than the duke they caught him fornicating with the duke’s wife; then he stated “he was an uptagrafft,” and then they proceeded to bring the duke’s daughter


Disclaimer: Up Syndrome definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.