Antiretroviral
Antiretroviral: An agent or process effective against a retrovirus. For example, a drug to treat HIV.
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- Antiretroviral therapy (ART)
Antiretroviral therapy (ART): Treatment that suppresses or stops a retrovirus. One of the retrovirus is the human immunodeficiency virus (HIV) that causes AIDS. Retroviruses are so named because they carry their genetic information in the form of RNA rather than DNA so that the information must be transcribed in “reverse” direction — from RNA into […]
- Antisense
Antisense: In molecular biology, the strand complementary to a coding sequence of a nucleic acid. Antisense DNA is the non-coding strand complementary to the coding strand in double-stranded DNA. The antisense strand serves as the template for messenger RNA (mRNA) synthesis. Antisense RNA is the non-coding strand complementary to a coding sequence of mRNA, a […]
- Antisense DNA
Antisense DNA: DNA normally has two strands, i.e., the sense strand and the antisense strand. In double-stranded DNA, only one strand codes for the RNA that is translated into protein. This DNA strand is referred to as the antisense strand. The strand that does not code for RNA is called the sense strand. Another way […]
- Antisense drug
Antisense drug: A medication containing part of the non-coding strand of messenger RNA (mRNA), a key molecule involved in the translation of DNA into protein. Antisense drugs hybridize with and inactivate mRNA. This stops a particular gene from producing the protein for which it holds the recipe. Antisense drugs have been developed or are “in […]
- Antisense mRNA
Antisense mRNA: An mRNA (messenger RNA) transcript that is complementary to endogenous mRNA. Antisense mRNA is the noncoding strand complementary to the coding sequence of mRNA. Introducing a transgene coding for antisense mRNA is a strategy used to block expression of a gene of interest.