Cowpox: A mild skin disease of milk cows, principally confined to the udder and teats, that can be contracted by people from milking an infected cow. Affected people develop vesicles (blebs), which break and form ulcers on the fingers (sometimes called ‘milkers’ nodules’). These usually heal without scarring.
Cox-1: Cyclooxygenase-1, an enzyme that acts to speed up the production of certain chemical messengers, called prostaglandins, in a variety of areas of the body such as the stomach, kidneys, and sites of inflammation. In the stomach, prostaglandins promote the production of a protective natural mucus lining. They also interact within certain cells that are […]
- Cox-1 inhibitor
Cox-1 inhibitor: An agent that inhibits the action of the enzyme cox-1 (cyclooxygenase-1). The common anti-inflammatory drugs such as aspirin, ibuprofen, and naproxen block the action of both cox-1 and cox-2. Cox-1 inhibitors can reduce inflammation, but they may also decrease the natural protective mucus lining of the stomach. Therefore, these medications can cause stomach […]
Cox-2: Cyclooxygenase-2, an enzyme that acts to speed up the production of certain chemical messengers, called prostaglandins that play a key role in in promoting inflammation. When cox-2 activity is blocked, inflammation is reduced. Unlike cox-1, cox-2 is active only at the site of inflammation, not in the stomach.
- Cox-2 inhibitor
Cox-2 inhibitor: An antiinflammatory drug that selectively blocks the cox-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors do not pose as great a risk of injuring the stomach or intestines as drugs that block cox-1. An example of a cox-2 […]
- Coxa valga
Coxa valga: Outward curvature of the hip. Malformation of the hip at birth, such as coxa valga, can increase one’s risk for development of osteoarthritis of the hip in later life