Dol: A unit of measurement of pain. The term dol was invented by James Hardy and his research colleagues Herbert Wolff and Helen Goodell at Cornell University where from 1950 to 1959, they carried out pioneering experiments on pain. Hasrdy, Wolff and Goodell used precisely calibrated radiant heat directed to the foreheads or hands of trained experimental subjects. They asked the subjects to report each “just noticeable difference” in the intensity of pain they experienced, and graphed their responses on the “dol” scale, in which one dol equals two “just noticeable differences.” The graphs showed the effectiveness of different analgesics in relieving the pain, and the physiologic responses with different intensities of pain. From the Latin word for pain, dolor.
Dolor: Pain, one of the four classic signs of inflammation together with calor, rubor, and tumor (heat, redness, and swelling, respectively).
- Domagk, Gerhard
Domagk, Gerhard: German physician and chemist (1895-1946) who discovered the first sulfa drug, prontosil, which ushered in the era of antibacterial medicine. For more information, see Prontosil.
Domain: In biomedicine, a discrete portion of a protein that has its own function. The combination of domains in a single protein determines the overall function of the protein.
Dominant: A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene […]
Donor: The giver of a tissue or an organ, such as a blood donor or kidney donor.