An atypical dementia characterized by a relentless dissolution of language with memory relatively preserved. The diagnosis of primary progressive aphasia is based on the presence of a progressive disorder of language, with preservation of other mental functions and of activities of daily living, for at least two years.
The features of primary progressive aphasia are distinct and different from those of typical Alzheimer’s disease. Different aspects of the activities of daily living are impaired and different sorts of intervention are required. Most people with primary progressive aphasia can take care of themselves, retain hobbies, and some can remain employed.
People with this disorder can learn sign language, and some find it useful to carry laminated cards that provide information to assist themselves and others in specific situations. Others benefit from voice synthesizers or personal computers that digitally store words and phrases. Evaluation by a speech therapist is useful for exploring alternative communication strategies.
Unlike patients with Alzheimer’s disease, who cannot retain new information in memory, patients with primary progressive aphasia can recall and evaluate recent events even though they may not be able to express their knowledge verbally. However, primary progressive aphasia is considered a type of dementia because it eventually does result ina gradual cognitive decline to the point where activities of daily living are compromised.
There is currently no effective drug or other treatment for this condition.
- Primary sclerosing cholangitis
A chronic disorder of the liver of uncertain cause in which the bile ducts within and outside of the liver become inflamed, thickened, scarred (sclerotic), and obstructed. This progressive process can in time destroy the bile ducts and lead to cirrhosis. Abbreviated PSC. PSC can occur by itself or in association with other diseases, including […]
- Primary teeth
The first teeth which are shed and replaced by permanent teeth. The first primary tooth comes in at about 6 months of age and the 20th and last primary tooth erupts at around 2 1/2 years of age. The primary teeth are replaced beginning usually at about age 6. Also called baby teeth, milk teeth, […]
- Primary tumor
A tumor that is at the original site where it first arose. For example, a primary brain tumor is one that arose in the brain as opposed to one that arose elsewhere and metastasized (spread) to the brain. The original tumor is sometimes called “the primary.”
- Primitive neuroectodermal tumor
Ewing tumor of bone; extraosseus Ewing tumor (tumor growing outside of the bone); primitive neuroectodermal tumor (PNET), also known as peripheral neuroepithelioma; and Askin tumor (PNET of the chest wall).
In embryology, organ or tissue in its earliest recognizable stage of development. Take, for example, the thyroid primordium. The plural is primordia. Borrowed directly from the Latin primordium (to begin), derived from the Latin words primus (first) + ordiri (to begin). Known also as the anlage or rudiment.