Transaminase clinical usage


Two of the better known enzymes in the transaminase class are serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT). Both SGOT and SGPT are normally found primarily in liver and heart cells, are released into the bloodstream as the result of liver or heart damage, and so serve as tests of the liver and heart. The levels of these transaminases are elevated by liver disease (for example, viral hepatitis) or by an insult to the heart (for example, a heart attack). Some medications can also raise the levels of these transaminases. The interpretation of elevated SGOT and SGPT levels depends upon the context and can necessitate additional clinical and laboratory information.

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  • Transaminase, serum glutamic oxaloacetic

    An enzyme that is normally present in liver and heart cells, and is released into blood when the liver or heart is damaged. Blood SGOT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise […]

  • Transaminase, serum glutamic pyruvic (SGPT)

    An enzyme that is normally present in liver and heart cells, and is released into blood when the liver or heart is damaged. Blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise […]

  • Transcranial

    Through the cranium. As, for example, in transcranial magnetic stimulation.

  • Transcranial magnetic stimulation

    Abbreviated TMS. A non-invasive technique that consists of a magnetic field emanating from a wire coil held outside the head. The magnetic field induces an electrical current in nearby regions of the brain. TMS was originally developed as a diagnostic tool for mapping brain function. It appears promising as a treatment for some neuropsychiatric conditions, […]

  • Transcription

    Making an RNA copy from a sequence of DNA (a gene). Transcription is the first step in gene expression.


Disclaimer: Transaminase clinical usage definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.