Locoregional anesthesia
Anesthesia that eliminates pain only in the region of the surgery. This may be done by a “spinal” in which an anesthetic agent is administered by lumbar injection. Locoregional anesthesia is in contrast to general anesthesia on the one hand and local anesthesia on the other.
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- Locoregional metastasis
Metastasis (spread) of a cancer only within the region in which it arose. In contrast to systemic metastasis.
- Locus
In genetics, the place a gene occupies on a chromosome. The plural is loci.
- Locus minoris resistentiae
Latin meaning a place of less resistance. A locus minoris resistentiae offers little resistance to microorganisms. For example, a damaged heart valve acts as a locus minoris resistentiae, a place where any bacteria in the bloodstream tend to settle. The concept of a locus minoris resistentiae is an old one but still a valid, useful […]
- LOD score
In genetics, a statistical estimate of whether two loci (the sites of genes) are likely to lie near each other on a chromosome and are therefore likely to be inherited together as a package. LOD stands for logarithm of the odds (to the base 10). A LOD score of three or more is generally taken […]
- Loeys-Dietz syndrome
An inherited syndrome characterized by aortic aneurysms and other blood vessel abnormalities in children. The condition is often associated with other birth defects. The aortic aneurysms of Loeys-Dietz syndrome are prone to rupture at a smaller size than other aneurysms, with early identification of the condition and surgical intervention critical for survival.