Latin meaning a place of less resistance. A locus minoris resistentiae offers little resistance to microorganisms.
For example, a damaged heart valve acts as a locus minoris resistentiae, a place where any bacteria in the bloodstream tend to settle.
The concept of a locus minoris resistentiae is an old one but still a valid, useful way of thinking.
- LOD score
In genetics, a statistical estimate of whether two loci (the sites of genes) are likely to lie near each other on a chromosome and are therefore likely to be inherited together as a package. LOD stands for logarithm of the odds (to the base 10). A LOD score of three or more is generally taken […]
- Loeys-Dietz syndrome
An inherited syndrome characterized by aortic aneurysms and other blood vessel abnormalities in children. The condition is often associated with other birth defects. The aortic aneurysms of Loeys-Dietz syndrome are prone to rupture at a smaller size than other aneurysms, with early identification of the condition and surgical intervention critical for survival.
The disease caused by the eye worm known as loa loa, a parasite that lives in humans and other primates. People contract the parasite when bitten by infected deer flies. The larvae of the worm enter the bloodstream and later develop into adult worms. Symptoms may not appear for months or years after the bite […]
- Library, genomic
A collection of clones that is made from a set of randomly generated overlapping DNA fragments and that represents the entire genome of an organism. Also known as clone bank.
- Library, cDNA
A collection of DNA sequences generated from mRNA (messenger RNA) sequences. This type of DNA library contains only DNA that codes for proteins and does not include any non-coding DNA.