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Syndrome, Pickwickian

The combination of obesity, somnolence (sleepiness), hypoventilation (underbreathing), and plethoric (red) face. The syndrome is so named because of the “fat and red-faced boy in a state of somnolency” that Charles Dickens described in his novel, The Pickwick Papers. (The same boy is thought by some experts possibly to have had the Prader-Willi syndrome).

Syndrome, piriformis

Irritation of the sciatic nerve caused by compression of the nerve within the buttock by the piriformis muscle. Typically, the pain of the piriformis syndrome is increased by contraction of the piriformis muscle, prolonged sitting, or direct pressure applied to the muscle. Buttock pain is common. The piriformis syndrome is one of the causes of […]

Syndrome, Pisa

A condition in which there is sustained involuntary flexion of the body and head to one side and slight rotation of the trunk so the person appears to lean like the Leaning Tower of Pisa. The Pisa syndrome is an adverse effect (a side-effect) of some medications. It occurs sometimes following the long-term use of […]

Syndrome, Poland

191, 1841). Poland became a celebrated surgeon and ophthalmologist but had to retire in 1867 due to a chronic cough. He died in 1872 at the age of 51 of “consumption of the lungs” (pulmonary tuberculosis). Although Poland could never have discovered this syndrome without George Elt, Mr. Elt has not been credited nor has […]

Systolic

The blood pressure when the heart is contracting. It is specifically the maximum arterial pressure during contraction of the left ventricle of the heart. The time at which ventricular contraction occurs is called systole. In a blood pressure reading, the systolic pressure is typically the first number recorded. For example, with a blood pressure of […]

Systole

The time period when the heart is contracting. The period specifically during which the left ventricle of the heart contracts. The final letter in “systole” is pronounced as a long “e” as in “lee.” The adjective for systole is systolic. The systolic pressure is specifically the maximum arterial pressure during contraction of the left ventricle […]

Systems biology

The study of biological systems taking into account the interactions of the key elements such as DNA, RNA, proteins, and cells with respect to one another. The integration of this information may be by computer.

Systemic-onset juvenile rheumatoid arthritis

A form of joint disease in children whose systemic signs and symptoms include high intermittent fever, a salmon-colored skin rash, swollen lymph glands, enlargement of the liver and spleen, inflammation of the lungs (pleuritis), and inflammation around the heart (pericarditis). The arthritis itself may not be immediately apparent, but in time it surfaces and may […]

Systemic therapy

Treatment that reaches cells throughout the body by traveling through the bloodstream.